Research Technician
Massachusetts General Hospital(MGH)

Boston, Massachusetts


GENERAL SUMMARY/ OVERVIEW STATEMENT:

A position is available for a laboratory technician to be a part of the Alzheimer's disease (AD) research team in the lab of Dr. Brad Hyman. The major goal of the lab is to study the molecular mechanisms and neuropathology of neurodegenerative changes in AD and related disorders to understand the pathophysiology of these diseases and improve diagnosis and treatment. More specifically to this position we are looking at the effect of the protein encoded by the greatest genetic risk factor for AD, apolipoprotein E, which is an immensely exciting area of AD research. The successful candidate will master the art of tissue culture, immunohistochemistry, western blotting, ELISA, microscopy, image analysis, and in vivo mouse work including surgery. The incumbent is expected to work both independently and as a team member with investigators, staff, fellows, and students; and will report directly to Dr. Brad Hyman and Dr. Rosemary Jackson.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

Please note, the functions below are representative of major duties that are typically associated with these positions. Specific responsibilities may vary based upon departmental needs. Similarly, not all duties that have been outlined will be assigned to each position.

  • Prepares basic solutions and performs base-level procedures as assigned (i.e. - pipetting, cell and tissue culture, etc.)
  • Maintains laboratory notebook
  • Understands and applies basic scientific techniques
  • Conducts analysis of results and may begin interpretation of results
  • Sets up and prepares routine experiments as directed
  • Prepares lab reagents, chemicals, instruments and equipment
  • May perform independent literature searches
  • Assists with organizing materials for publication or presentation
  • Maintains and orders supplies
A Research Technician II performs the duties of a Research Technician I (above) and may also:
  • Execute protocols of non-routine experiments
  • Assist the PI(s) with determining the most suitable methodology
  • Perform basic design and modification of protocols
  • Calculate, transcribe and analyze data
  • Prepare and present reports
  • Organize and summarize acquired data, using scientific and statistical techniques.
  • Organize and/or draft material for the preparation of research papers, manuscripts and other documents for publication and/or presentation.
  • Participate in the design of experiments or field work.

SKILLS/ABILITIES/COMPETENCIES REQUIRED:
  • Ability to work independently and as a team member
  • Good communication skills
  • Computer literacy
  • Working knowledge of clinical research protocols
  • Ability to perform multiple tasks independently
The Research Technician II should also possess:
  • Analytical skills and the ability to resolve technical problems
  • Ability to interpret acceptability of data results
  • Working knowledge of data management programs
  • Demonstrated competence in research techniques and methodologies


Qualifications
EDUCATION:
  • Bachelor's degree required.

EXPERIENCE:
  • New graduates with some lab experience (via course work, internships, etc.) or those without any prior research experience will be considered for the Research Technician I position outlined above.
  • Those with a minimum of 1 year of directly related work experience will be considered for a Research Technician II position.

SUPERVISORY RESPONSIBILITY (if applicable):
  • A Research Technician II may serve as a team leader to lab assistants and Research Technician I's.


EEO Statement
Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.



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