Biologist
CAMRIS

Bethesda, Maryland

This job has expired.


Overview

We are seeking a Biologist to support the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, MD. Our NIAID professional, technical, and scientific support personnel are part of a team focused on positively impacting millions of lives around the world. Candidates will work at a diverse and vibrant NIAID worksite to directly support ongoing research activities as a contractor team member. Take the next big step in your career and apply below to help us make a difference.

CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today's most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs.

Our employees enjoy a diverse, collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad.

Responsibilities

  • Produce and purify viral proteins and monoclonal antibodies as research reagents using transient transfection of mammalian cells or by expansion of stable cell lines or pools.
  • Develop high-throughput and automated protein purification methodology, if required.
  • Act as the Scientific Technical Lead and advise on the design and development of viral proteins and monoclonal antibodies.
  • Test antigenicity and specificity of proteins produced through Meso Scale Discovery, Carterra and/or Octet affinity measurements.
  • Culture and maintain cell lines.
  • Organize and maintain protein inventories.
  • Participate in project and laboratory meetings.
  • Locate and review literature pertinent to projects and to identify/modify the most applicable protocols and methods for experiments.
  • Trouble shoot assays and adjust scientific methodology to correct problems or deficiencies in a research project, experiment, or trial.
  • Maintain accurate laboratory records to ensure proper retention of scientific data. Provide oversight and be the Scientific Technical Lead for all protein production performed by the group.
  • Serve as a subject matter expert on development, validation and deployment of assays and methods for evaluation of antibody-protein interactions.
  • Train other contractors and students in methodologies related to protein production and purification and antibody evaluation. Assist the Federal Task Leader in designing and implementing training guidelines for instrumentation and assays.
  • Analyze and communicate complex data sets to internal and external groups.
  • Develop and maintain collegial, collaborative relationships with colleagues in the VRC research groups.


Qualifications

  • Master's degree with relevant experience or Bachelor's degree in Biology, Life Sciences or a related discipline with 3 years of specialized experience.
  • Minimum of two (2) years of related experience.
  • Knowledge of viral and vaccine immunology.
  • Basic computer skills to include MS Word, Excel, and PowerPoint.
  • Background in biology, chemistry, biochemistry and/or biophysics.
  • Ability to multi-task in a high-volume fast paced work environment.
  • Experience with mammalian cell culture for both anchorage dependent and suspension cell culture.
  • Experience with purification of eukaryotic proteins such as IMAC, affinity purification, ion exchange chromatography, FPLC and HPLC with a demonstrated ability to develop optimal methods of purification to obtain high quality proteins.
  • Expertise in molecular biology and design of expression vectors, transfection techniques, screening of cells expressing recombinant proteins and knowledge of classical purification methods such as ammonium sulfate precipitation.
  • Experience with biomolecular interactions using ELISA as well as the use of label-free methods such as BioLayer Interferometry and SPR.
  • Familiarity with scientific 2D graphing and statistics software (GraphPad Prism, etc.).
  • Familiarity with protein structure modeling programs such as Pymol preferred.
  • Excellent communication skills, both written and verbal.
  • Knowledge of laws, regulations, policies, and guidelines and ethics that govern research.
  • Demonstrates knowledge of maintaining accurate and detailed records.
  • Demonstrates knowledge of proper laboratory disposal methods and safety procedures.


CAMRIS International LLC offers competitive salaries and comprehensive benefits. Please submit your resume online at www.CAMRIS.com . CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.

Some positions or sites may require that the incumbent be fully vaccinated against COVID-19. Proof of vaccination may be required.

Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.


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